▲>>2388811
Ну вот ты щас рофлишь, да?
>The task oftesting was assigned to the FDA by the US Army. Accordingly, the FDA tested more than a hundred prescriptions and over-the-counter medications and observed that 90 per cent of the expired drugs were still safe and potent; the oldest drug tested had expired 15 years back at the time of testing. The study pointed out that the expiry date did not really indicate a point at which the medication was no longer effective or had become unsafe to use
>An issue of The Medical Letter quoted not only the above study but also of others showing expensive medications like Amantadine and Rimantadine maintaining their stability after storage for 25 years under ambient conditions and retained full anti-viral activity after boiling and holding at 65-85° C for several days. Regenthal and coauthors in 2002 observed that the drug Theophylline, in tablet form, showed 90 per cent stability even after 30 years beyond the expiry date.
>In a recent article, Richard Altschuler has quoted Francis Flaherty, a former director of the testing programme of FDA saying, “expiration dates put on by manufacturers, typically have no bearing on whether a drug is usable for longer. A drug maker is required to prove only that a drug is still good on whatever expiration date the company chooses to set. The expiration date doesn't mean, or even suggest, that the drug will stop being effective after that, nor that it will become harmful. Manufacturers put expiration dates on for marketing, rather than scientific reasons. It’s not profitable for them to have products on a shelf for 10 years. They want turnover." Mr Altschuler has also quoted Joel Davis, who has been former FDA expiration-date compliance chief as “with a handful of exceptions - notably nitroglycerin, insulin, and some liquid antibiotics - most drugs are probably as durable as those the agency has tested for the military. Most drugs degrade very slowly. In order to maintain the potency and safety of the drugs, however, it is mandatory that these are stored in a refrigerator and not exposed to direct sunlight, heat and humidity.”
>In the light of the foregoing information, the question remains as to what should be done with the drugs that have passed the expiration dates mentioned by the drug manufacturer, especially in the case of bulk purchasers in the government sector. The US military has devised a programme of extension of shelf life of the expired drugs by getting them tested from the FDA. It may be worthwhile for the developing countries also to explore the possibility of identifying/ developing such national organisations like FDA so that if the need arises, such shelf extension programmes can be undertaken.
А швитые вон говорят, что для многих таблетосов это просто маркетинг.